Methandienone injection is a modified form of testosterone. This anabolic steroid has a much weaker relative binding affinity for the androgen receptor than testosterone, but at the same time displays a much longer half-life and lower affinity for serum-binding proteins in comparison. These features allow Methandienone injection from Magnus Pharmaceuticals to be a very potent anabolic steroid in spite of a weaker affinity for receptor binding. Recent studies have additionally confirmed that its primary mode of action involves interaction with the cellular androgen receptor.
Methandienone Injection Side Effects (Estrogenic)
Methandienone injection from Magnus Pharmaceuticals is aromatized by the body, and is a moderately estrogenic steroid. Gynecomastia is often a concern during treatment, and may present itself quite early into a cycle (particularly when higher doses are used). At the same time water retention can become a problem, causing a notable loss of muscle definition as both subcutaneous water retention and fat levels build. Sensitive individuals may therefore want to keep the estrogen under control with the addition of an anti-estrogen such as Nolvadex and/or Proviron.
One may alternately use an aromatase inhibitor like Anastrozole, which is a more effective remedy for estrogen control. Aromatase inhibitors, however, can be quite expensive in comparison to standard estrogen maintenance therapies, and may also have negative effects on blood lipids.
A key dissimilarity seems to lie in the tendency for estrogenic side effects. Boldenone undecylenate is known to be quite mild in this regard, and users commonly take this drug without the need to add an anti-estrogen. Methandienone injection (methandrostenolone) is much more estrogenic, often necessitating anti-estrogen use.
Methandienone Injection Side Effects (Androgenic)
Although classified as an anabolic steroid, androgenic side effects are still common with this substance. This may include bouts of oily skin, acne, and body/facial hair growth. Anabolic/androgenic steroids may also aggravate male pattern hair loss. Individuals sensitive to the androgenic effects of Methandienone injection from Magnus Pharmaceuticals may find a milder anabolic such as Nandrolone Decanoate to be more comfortable.
Women are additionally warned of the potential virilizing effects of anabolic/androgenic steroids. These may include a deepening of the voice, menstrual irregularities, changes in skin texture, facial hair growth, and clitoral enlargement.
Methandienone Injection Side Effects (Cardiovascular)
Anabolic/androgenic steroids can have deleterious effects on serum cholesterol. This includes a tendency to reduce HDL (good) cholesterol values and increase LDL (bad) cholesterol values, which may shift the HDL to LDL balance in a direction that favors greater risk of arteriosclerosis.
Anabolic/androgenic steroids may also adversely affect blood pressure and triglycerides, reduce endothelial relaxation, and support left ventricular hypertrophy, all potentially increasing the risk of cardiovascular disease and myocardial infarction.
To help reduce cardiovascular strain it is advised to maintain an active cardiovascular exercise program and minimize the intake of saturated fats, cholesterol, and simple carbohydrates at all times during active AAS administration. Supplementing with fish oils (4 grams per day) and a natural cholesterol/antioxidant formula such as Lipid Stabil or a product with comparable ingredients is also recommended.
Methandienone Injection Side Effects (Testosterone Suppression)
All anabolic/androgenic steroids when taken in doses sufficient to promote muscle gain are expected to suppress endogenous testosterone production. Methandienone injection from Magnus Pharmaceuticals is no exception, and is noted for its strong influence on the hypothalamic-pituitary-testicular axis. Clinical studies giving 15 mg per day to resistance-training males for 8 weeks caused the mean plasma testosterone level to fall by 69%. Without the intervention of testosterone stimulating substances, testosterone levels should return to normal within 1-4 months of drug secession. Note that prolonged hypogonadotrophic hypogonadism can develop secondary to steroid abuse, necessitating medical intervention.
Methandienone Injection Administration (Men)
For performance improvement purposes, a daily dose 50 mg is most common, and typically produces very dramatic results. Some venture even higher in dosage, but this practice usually leads to a more profound incidence of side effects, and is generally discouraged. Methandienone injection from Magnus Pharma stacks well with a variety of other steroids. It is noted to mix particularly well with the mild anabolic Nandrolone decanoate, for example. Together one can expect exceptional muscle and strength gains, with side effects not much worse than one would expect from Methandienone alone. The recommended cycle length is 6-8 weeks.
For sheer mass, a long-acting testosterone ester like Testosterone enanthate or Testosterone cypionate can be used. With the high estrogenic/androgenic properties of this androgen, however, side effects should be more pronounced. Gains would be pronounced as well, which usually makes such an endeavor worthwhile to the user.
Being moderately androgenic, Methandienone injection from Magnus is really only a popular steroid with men. When used by women, strong virilization symptoms are possible. Therefore, it is generally not recommended for women.